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Igf 1 signalling from sugar

Ronaldo

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I saw on TikTok this dude eating multiple pies full of sugar for igf 1 signalling does it work and is it true
 
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oh my fucking god
Screenshot_20251122_085441_TikTok (1).jpg
 

Ronaldo

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explain the entire process to me without using chatgpt/external sources.
IGF-1 binds to its receptor. The receptor’s tyrosine kinase domains autophosphorylate. Docking proteins attach. Two major cascades activate: PI3K-AKT and RAS-RAF-MEK-ERK.


PI3K converts PIP2 to PIP3. AKT binds PIP3 and becomes activated. AKT increases protein synthesis through mTOR and reduces apoptosis.


RAS-RAF-MEK-ERK drives transcriptional programs for growth, cell-cycle progression, and proliferation.


Negative regulation occurs through IGF-binding proteins, receptor internalisation, and phosphatases that reverse phosphorylation states.
 

Dexter

Low IQ Mentalcel
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IGF-1 binds to its receptor. The receptor’s tyrosine kinase domains autophosphorylate. Docking proteins attach. Two major cascades activate: PI3K-AKT and RAS-RAF-MEK-ERK.


PI3K converts PIP2 to PIP3. AKT binds PIP3 and becomes activated. AKT increases protein synthesis through mTOR and reduces apoptosis.


RAS-RAF-MEK-ERK drives transcriptional programs for growth, cell-cycle progression, and proliferation.


Negative regulation occurs through IGF-binding proteins, receptor internalisation, and phosphatases that reverse phosphorylation states.
yeah im supposed to believe you wrote that in 1 min
if you truly knew what the process was you wouldn't ask that question in the first place you retard
 

Ronaldo

ORG reject, time to move to GG
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yeah im supposed to believe you wrote that in 1 min
if you truly knew what the process was you wouldn't ask that question in the first place you retard
Ok bro
 
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