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Increlex/Mecasermin Questions

Perfectus

Iron
Joined
Nov 27, 2025
Posts
6
Reputation
7
Hello I hope you're all doing well.

I have access to actual IGF-1 (Mecasermin/Increlex) but I have a few questions that I hope I can get answers to.
1. How do I dose it. I've heard on the certain bodybuilding forums that Increlex should be taken twice a day (once in the morning once at night) at around 25 mcg a day although if anyone has other information they can share I'd appreciate it. (What I mean is, is this optimal?)
2. Should I use hGH with it or would that just be cope?
3. What ancillaries should I take so my organs don't grow?
4. Is it localized or can I inject it anywhere and expect bone growth. From what I understand so f
5. Yes my growth plates are open, but will this even affect my bones? (It's typically used by bodybuilders, not by people who want to get taller)
6. What else should I take alongside these (the price doesn't matter and no I'm not from the🧃 people)?
- Increlex
- hGH (I will start at 4 IU and work up to 8 IU by adding two IU every month because I don't want Carpal Tunnel)
- Letrozole (I think I heard from Vigorous Steve that the full letrozole pill crashes your estrogen to much and that I should use a milder AI besides letrozole. If I could get help here that would be nice)
- Berberine is a supplement but I will take it so I don't get diabetes.
7. Biomaxx Biomaxx I have access to (or at least I think I have access to) Romosozumab, Abaloparatide, Teriparatide, and Kartogenin. If you do recommend me to use these, how do I dose them?

Repping anyone who helps. If things go well I will update you all when I get my stuff.
 

Biomaxx

Absolutely bonkers mate.
Joined
Oct 12, 2025
Posts
1,624
Reputation
2,925
Hello I hope you're all doing well.

I have access to actual IGF-1 (Mecasermin/Increlex) but I have a few questions that I hope I can get answers to.
1. How do I dose it. I've heard on the certain bodybuilding forums that Increlex should be taken twice a day (once in the morning once at night) at around 25 mcg a day although if anyone has other information they can share I'd appreciate it. (What I mean is, is this optimal?)
2. Should I use hGH with it or would that just be cope?
3. What ancillaries should I take so my organs don't grow?
4. Is it localized or can I inject it anywhere and expect bone growth. From what I understand so f
5. Yes my growth plates are open, but will this even affect my bones? (It's typically used by bodybuilders, not by people who want to get taller)
6. What else should I take alongside these (the price doesn't matter and no I'm not from the🧃 people)?
- Increlex
- hGH (I will start at 4 IU and work up to 8 IU by adding two IU every month because I don't want Carpal Tunnel)
- Letrozole (I think I heard from Vigorous Steve that the full letrozole pill crashes your estrogen to much and that I should use a milder AI besides letrozole. If I could get help here that would be nice)
- Berberine is a supplement but I will take it so I don't get diabetes.
7. Biomaxx Biomaxx I have access to (or at least I think I have access to) Romosozumab, Abaloparatide, Teriparatide, and Kartogenin. If you do recommend me to use these, how do I dose them?

Repping anyone who helps. If things go well I will update you all when I get my stuff.
If this is for hieght growth then hgh is the only way to go, any igf1 in the body that isn't produced in the liver tends to be what's called "free" igf where it float into any nearby cells as its not carried by igfpb causing high risks of cancer cells growth and js strange growth patterns in general . (Im not 100% sure abt increlex dosing Mandy Mandy ) but if your taking it for different reasons its likely different dosing.

Don't start so low on hgh, 4iu Is way below natural production. I jumped straight onto 7 then moved onto 10 and ive been fine except some bloat anf occasional joint pain.

There's not much you can do for organ enlargement without js ruining the hgh/increlex effects ( Mandy Mandy Can you confirm ??)

For effecting ur bones im gonna only use the example of hgh. Yes it will 100% effect your bones as its proven to be anabolic to bone which is why I personally suggest alot of mechanical loading whilst on these compounds

DONT TAKE LETROZOLE. It will crash ur levels way to harshly and will make you retarded, depressed and ill . Take a low dose aromasin instead

If u have a source for abalo dm me we can sort stuff out
 

Mandy

Messiah
Joined
Nov 11, 2025
Posts
154
Reputation
260
If this is for hieght growth then hgh is the only way to go, any igf1 in the body that isn't produced in the liver tends to be what's called "free" igf where it float into any nearby cells as its not carried by igfpb causing high risks of cancer cells growth and js strange growth patterns in general . (Im not 100% sure abt increlex dosing Mandy Mandy ) but if your taking it for different reasons its likely different dosing.

Don't start so low on hgh, 4iu Is way below natural production. I jumped straight onto 7 then moved onto 10 and ive been fine except some bloat anf occasional joint pain.

There's not much you can do for organ enlargement without js ruining the hgh/increlex effects ( Mandy Mandy Can you confirm ??)

For effecting ur bones im gonna only use the example of hgh. Yes it will 100% effect your bones as its proven to be anabolic to bone which is why I personally suggest alot of mechanical loading whilst on these compounds

DONT TAKE LETROZOLE. It will crash ur levels way to harshly and will make you retarded, depressed and ill . Take a low dose aromasin instead

If u have a source for abalo dm me we can sort stuff out
Not experienced with increlix,don’t know much about it but I’ll see this thread.
 

Mandy

Messiah
Joined
Nov 11, 2025
Posts
154
Reputation
260
Hello I hope you're all doing well.

I have access to actual IGF-1 (Mecasermin/Increlex) but I have a few questions that I hope I can get answers to.
1. How do I dose it. I've heard on the certain bodybuilding forums that Increlex should be taken twice a day (once in the morning once at night) at around 25 mcg a day although if anyone has other information they can share I'd appreciate it. (What I mean is, is this optimal?)
Like Biomaxx Biomaxx said,it’s not ideal to use it.
2. Should I use hGH with it or would that just be cope?
Just use the HGH as a main.
3. What ancillaries should I take so my organs don't grow?
People exxagerate organ growth,risk increases after 12-14IU
4. Is it localized or can I inject it anywhere and expect bone growth. From what I understand so f
No idea what you’re talking here,if it’s GH then no. IGF-1 DES works like that.
5. Yes my growth plates are open, but will this even affect my bones? (It's typically used by bodybuilders, not by people who want to get taller)
Only if you have excess IGF-1 and a upregulation in the ER-a receptor.
6. What else should I take alongside these (the price doesn't matter and no I'm not from the🧃 people)?
- Increlex
- hGH (I will start at 4 IU and work up to 8 IU by adding two IU every month because I don't want Carpal Tunnel)
- Letrozole (I think I heard from Vigorous Steve that the full letrozole pill crashes your estrogen to much and that I should use a milder AI besides letrozole. If I could get help here that would be nice)
- Berberine is a supplement but I will take it so I don't get diabetes.
7. Biomaxx Biomaxx I have access to (or at least I think I have access to) Romosozumab, Abaloparatide, Teriparatide, and Kartogenin. If you do recommend me to use these, how do I dose them?
All trash synergy. If you’re not on test dont play with AI’s. On test dosages 200-400mg you should use 6.25mg of Aromasin EOD. Berberine lowers systemic IGF-1,just like Metformin so no. Get rid of the increlex,Use 8IU of GU with 15IU lantus insulin,40mcg T4 and if you can get real anavar then 5-10mg of that.
Repping anyone who helps. If things go well I will update you all when I get my stuff.
Thanks
 
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