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Guide Retatrutide dosage guide

morty

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RETATRUTIDE: THE FAT LOSS NUCLEAR OPTION


Retatrutide (LY3437943) is the current "God Tier" compound for cutting. Unlike Semaglutide (Ozempic) or Tirzepatide (Mounjaro), this is a TRIPLE agonist (GLP-1, GIP, and Glucagon). The Glucagon component increases energy expenditure, meaning you burn fat just by existing, not just by starving.


I. THE MECHANISM


1. GLP-1: Smashes appetite. You simply forget to eat.


2. GIP: Improves insulin sensitivity and nutrient partitioning.


3. Glucagon: The game changer. Increases thermogenesis and resting metabolic rate. This is why Retatrutide mogs Tirzepatide.


II. RECONSTITUTION PROTOCOL


You will receive this as a lyophilized (freeze-dried) powder in a vial. You cannot inject dust. You need Bacteriostatic Water (BAC Water).


Step 1: Pop the cap off the vial and wipe the rubber stopper with an alcohol swab.


Step 2: Take your syringe and draw up 1ml to 2ml of BAC water (depending on vial size, usually 2ml is easier for math).


Step 3: Slowly inject the water into the vial. Aim for the glass wall, not the powder directly.


Step 4: DO NOT SHAKE IT. Peptides are fragile. Gently swirl the vial in a circular motion until clear.


Step 5: Store in the fridge immediately. It degrades at room temperature once mixed.


III. DOSAGE TIERS (THE TITRATION LADDER)


Do not ego lift your dosage. Retatrutide is potent. If you start high, you will spend 3 days vomiting. The half-life is ~6 days, so you dose ONCE weekly.


Weeks 1-4 (Acclimation):


Dosage:
2 mg per week.


Goal: Assess tolerance. If you feel zero hunger and slight nausea, stay here.


Weeks 5-8 (The Ramp):


Dosage:
4 mg per week.


Goal: Fat melting phase begins. Most users stay here if side effects get heavy.


Weeks 9-12 (High Performance):


Dosage:
6 mg to 8 mg per week.


Goal: Deep deficit. Only go here if 4 mg has stopped working.


Weeks 13+ (The Ceiling):


Dosage:
10 mg to 12 mg per week.


Warning: This is clinical trial max territory. Diminishing returns hit hard here.


IV. SIDE EFFECTS & MITIGATION


1. Heart Rate Spike


Retatrutide is known to increase resting heart rate by 10-15 BPM due to the Glucagon activity.


Fix: Watch your cardio intensity. If resting HR goes over 100, drop the dose.


2. Gastrointestinal Nuke


Nausea, diarrhea, sulfur burps.


Fix: Eat clean. Greasy food + Retatrutide = Disaster pants. Inject in the thigh rather than stomach to potentially reduce nausea.


3. The Flatness (Glycogen Depletion)


You will look flat and small because you aren't eating carbs.


Fix: Keep electrolytes high (Sodium/Potassium). Don't panic, the fullness comes back when you eat carbs again.


V. GYMCEL PROTOCOL: KEEPING THE GAINS


The danger with Reta is you lose weight so fast you burn muscle tissue. You must force-feed protein.


1. Protein Priority


You will not be hungry. You must drink your protein if you can't chew it. Aim for 1g per lb of bodyweight minimum. If you fail this, you will end up "skinny fat."


2. Lift Heavy


Do not switch to high rep "toning" work. Lift heavy (low reps, high intensity) to signal your body to keep the muscle tissue.


3. Cycle Length


Run for 12-16 weeks maximum. Afterward, taper off to avoid a massive hunger rebound.


Do not be an idiot.
 
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