Guide Full dive into fgfr3 inhibitors (3 Viewers)

[Mtn_hell]

this

so too short and bad topic gotcha

 

[nineteen]

so too short and bad topic gotcha

it’s a good topic, it’s just shorter than it should be and could be formatted better

 

[Baal]

this

nah hes lying to you OP, he just wants what he thinks is aesthetically pleasing which is just rainbow coours and shit, then you get BOTB, just dnr mods like cameron does and post your shit anyway without giving a fuck, who cares its good info regardless

 

[Godveil Heir]

ahhh ok mb im a bit stupid deffo will have a look ty for the advice

keep up the work if you like it tbh

Almost everyone fails to research and create guides for the first few months.
With time, you will learn and acquire the skills. I recommend collaborating with established users to learn more.

 

[Mtn_hell]

it’s a good topic, it’s just shorter than it should be and could be formatted better

would be better with spoilers yh idk what else to do about this topic ty tho

 

[Mtn_hell]

keep up the work if you like it tbh

Almost everyone fails to research and create guides for the first few months.
With time, you will learn and acquire the skills. I recommend collaborating with established users to learn more.

yh deffo js need another topic next one will prolly be side compounds

 

[XvideosDemon]

In my attempt of a BOTB thread I will dive into fgfr3 inhibitors.

This thread will cover:

-What they are

-How they can help

-Studies

-Side effects




fgfr3 inhibitors are usually oral tablets designed to block fibroblast growth factor receptor 3 signalling (FGFR3). Fgfr 3 common FDA approved drugs are erdafitnib and pemigatinib. Pemigatinib is commonly used for treating bile duct cancer and erdafitinib is commonly used for treating cancer lining the bladder.
The overall response rate for fgfr 3 is approximately 20 - 40%.


Another purpose of fgrfr 3 inhibitors is to regulate bone growth which is where they can help.

FGFR 3 acts like a brake when growing bones however it is not negative. When FGFR 3 is strong bone growth slows, when its blocked growth plates can produce more cartilage therefore creating longer bones.

Therefore in theory FGFR 3:

- Increase bone growth

-Slightly affect limb proportions and help frame

-Influence facial skull growth during development

-Help with height


However, this works best while growth plates are open. When they close (16 - 18 females, & 18-21 males) growth from these drugs become impossible. Neither will it help sculpt the skull in adults only teenagers.


Studies show that with daily injections before growth plates close height can grow between 1.5 - 2 cm every year.

Studies also show:

- Forward growth of the midface

- Better orbital positioning

-Better chin projection

These changes are small yet noticeable

View attachment 36277


Although we may not care here are some side effects which can be experienced while taking fgfr3 inhibitors

Injection site reactions such as swelling, redness, itching with an approx. 85% chance of happening

Immunity to the drug with 35% chance

vomiting with 27% cahnce

joint pain with 15% chance

low blood pressure with 13% chance




This is my first time making a proper thread like this excluding my eye area one ty for reading go ascend. Lmk if I missed anything or any improvements for future threads Aryan Incel Circadex Godveil Heir ramus

Spoilers more info and just better writing and coloring your words in certain areas

 

[nineteen]

keep up the work if you like it tbh

Almost everyone fails to research and create guides for the first few months.
With time, you will learn and acquire the skills. I recommend collaborating with established users to learn more.

 

[Mtn_hell]

nah hes lying to you OP, he just wants what he thinks is aesthetically pleasing which is just rainbow coours and shit, then you get BOTB, just dnr mods like cameron does and post your shit anyway without giving a fuck, who cares its good info regardless

yh knowing some1 read and learned from my thread is good enough for me

 

[Baal]

yh deffo js need another topic next one will prolly be side compounds

add this onto that thread aswell, format it well, you'll get far

 

[nineteen]

Godveil Heir how do you feel about the whole eddie situation?

 

[XvideosDemon]

keep up the work if you like it tbh

Almost everyone fails to research and create guides for the first few months.
With time, you will learn and acquire the skills. I recommend collaborating with established users to learn more.

Well put tbh

 

[Mtn_hell]

Spoilers more info and just better writing and coloring your words in certain areas

w advice will learn how to do that

 

[Baal]

w advice will learn how to do that

ly bhai, remember you from way back, good user, so didn't want to troll on u, keep it up man

 

[Godveil Heir]

@Godveil Heir how do you feel about the whole eddie situation?

Iirc he was an idiot and I banned him afterwards.

I don't think you should keep cyberbullying him with his pictures tbh, let him go

 

[Mtn_hell]

ly bhai, remember you from way back, good user, so didn't want to troll on u, keep it up man

how far back lol will deffo try harder and take this info on board ty all sm next thread can hopefully be better

 

[Baal]

Iirc he was an idiot and I banned him afterwards.

I don't think you should keep cyberbullying him with his pictures tbh, let him go

 

[Baal]

how far back lol will deffo try harder and take this info on board ty all sm next thread can hopefully be better

as soon as i joined tbh

 

[Mtn_hell]

as soon as i joined tbh

I rate it

 

[XvideosDemon]

Iirc he was an idiot and I banned him afterwards.

I don't think you should keep cyberbullying him with his pictures tbh, let him go

Then what will we make fun of ?

He’s a retard who should be remember for being retarted yes I do know that the only things I do and say on here aren’t the most high iq things you’ll see but Eddie is truly one of a kind joke it should be remembered even tho yes at sum point we might stop he should still be known for what he’s done

 

[Mtn_hell]

Then what will we make fun of ?

He’s a retard who should be remember for being retarted yes I do know that the only things I do and say on here aren’t the most high iq things you’ll see but Eddie is truly one of a kind joke it should be remembered even tho yes at sum point we might stop he should still be known for what he’s done

it was acc so fucking funny how he thought that was a good picture. him in a maccies looking down at the camera asking for a rating holy shit.

 

[XvideosDemon]

it was acc so fucking funny how he thought that was a good picture. him in a maccies looking down at the camera asking for a rating holy shit.

What I’m saying that’s why he needs to be remembered

 

[Mtn_hell]

What I’m saying that’s why he needs to be remembered

new logo for gg

 

[Synapzyzz]

brotal fail

 

[GatorBait]

Shit thread cl