Mogs LOXO-435 (1 Viewer)

[Razi]

say his name nigga bros not voldemort

I just said that because i didn’t think about anyone tbh so idk just think about someone and thats big dawg

 

[Perfectionist]

love you bhai
billions must learn, we ascend together, theres way more smarter people out there, like in hyderabad slums

What a fucking Chad

 

[birthdefect]

I just said that because i didn’t think about anyone tbh so idk just think about someone and thats big dawg

who big dawg

 

[Razi]

who big dawg

Read what I wrote there is no big dawg

 

[Perfectionist]

who big dawg

You are

 

[birthdefect]

You are

ladies ladies chill

Read what I wrote there is no big dawg

yo i lowkey cannot comprehend what you wrote, probably my fault
need some nootropics

 

[Biomaxx]

3rd place sucks doesn’t it?

 

[Perfectionist]

ladies ladies chill

yo i lowkey cannot comprehend what you wrote, probably my fault
need some nootropics

Fym ladies chill im a man,just glazing your ahh

 

[Razi]

ladies ladies chill

yo i lowkey cannot comprehend what you wrote, probably my fault
need some nootropics

Yeh you need high iq to understand what I type
But I’ll say that you’re close to big dawg I like your stuff you just don’t post a lot

 

[Perfectionist]

ladies ladies chill

yo i lowkey cannot comprehend what you wrote, probably my fault
need some nootropics

Bhai you need to do some meditation or sum

 

[Biomaxx]

love you bhai
billions must learn, we ascend together, theres way more smarter people out there, like in hyderabad slums

Slums is a peculiar place, humbled me

 

[Perfectionist]

Yeh you need high iq to understand what I type
But I’ll say that you’re close to big dawg I like your stuff you just don’t post a lot

Indirect compliment but thanks

 

[Tismo]

You're 1st place bhai

nigga how about you chill a bit you are taking my place as #1 razi glazer

 

[Biomaxx]

say his name nigga bros not voldemort

Zynx

 

[Perfectionist]

Bhai you need to do some meditation or sum

Like Cameron in the slums of Iran where yahu bhai is trying to ascend to true bomber

 

[Perfectionist]

nigga how about you chill a bit you are taking my place as #1 razi glazer

I've been glazing him since he joined nigger

 

[Biomaxx]

1 Rep farm pls

 

[Tismo]

I've been glazing him since he joined nigger

doesn't matter i overtook you

 

[Perfectionist]

I've been glazing him since he joined nigger

I glazed everyone here, other than the greys and low IQ niggas (bacland is an exception)

 

[Perfectionist]

doesn't matter i overtook you

Yeah I've been inactive for some time

 

[Tismo]

1 Rep farm pls

sorry for farming on your high iq post bhai

 

[birthdefect]

Zynx

new name to me

Fym ladies chill im a man,just glazing your ahh

ladies ladies one at a time

Slums is a peculiar place, humbled me

i dont really trust the use of hdaci tbh
computational is a clever guy tho

 

[Biomaxx]

new name to me

i dont really trust the use of hdaci tbh
computational is a clever guy tho

I should get more active in slums, things to be learnt

Zynx was old user here who straight hated me, pretty sure he was high iq

Ogre_cel was pretty high iq

 

[birthdefect]

I should get more active in slums, things to be learnt

Zynx was old user here who straight hated me, pretty sure he was high iq

Ogre_cel was pretty high iq

yea you should tbh, i speak there sometimes when i remember i have brooootalbirthdefect as an account

 

[Biomaxx]

yea you should tbh, i speak there sometimes when i remember i have brooootalbirthdefect as an account

Yes, I went to add u and you were already there

 

[birthdefect]

Bhai you need to do some meditation or sum

nah just tired

Yes, I went to add u and you were already there

yea bruh i thought you were gonna add me into some secret biomaxxing cult

 

[Neurogenic]

could LOXO-435 be the best option for fgfr3 inhibtion ?

Patented by LILLY, LOXO-435 is a highly selective FGFR3 inhibitor

If you are unsure of what fgfr3 does-
https://looksmax.gg/threads/fgfr3-inhibtion-epiphyseal-plates-and-bone-growth.19180/


LOXO-435 is confined to oncologic trials, no pediatric or skeletal growth studies have been initiated.

comparisons
​

Safety. Sides. Efficacy.

​

LOXO	high	very low	high
VORS	high	near to none	mid
ERDA	low	very high	high
INFI	mid	mid	high

View attachment 38569

Loxo-435
View attachment 38568
LOXO-435 is the most selective inhibitor studied to date. 361-fold selectivity over FGFR1 and 66-fold over FGFR2 .
This matters because pan-FGFR inhibitors (erdafitinib, infigratinib) hit FGFR1/2/4 and cause body wide toxicities, skin disorders, phosphatemia and more.

Unlike vosoritide and meclozine, which act indirectly via the CNP/cGMP pathway or analogous pathways, LOXO-435, as a direct small molecule inhibitor of the FGFR3 kinase, binds the receptor directly.
(Its direct)

Loxo is oral and taken twice a day (once may be adequate for plates). Around 100mg a day. Theoretically a 2 month onset

View attachment 38567View attachment 38570

Loxo imo, a very promising inhibitor
Highly effective
Highly selective
Direct
Cheap
But long onset

Studies
https://share.google/upuke5VGU4FyoD2bl
https://share.google/skUVinxfXwPurjQmt

https://aacrjournals.org/mct/articl...scovery-of-a-highly-potent-and?sharetype=link


Short thread ik
Yall think ive stepped up my content recently ?

@Dexter birthdefect carbon @Synapse Mandy tmpll XvideosDemon 9Dino Fram3Let 6ft1Cheat Tismo determinism H Hyporoxin brownkeephittin
​

Until next time
biomaxx

u have a source for it?

 

[Biomaxx]

Im a gay little chubby boy

???

 

[Neurogenic]

???

i asked if u have a source for it

 

[Neurogenic]

?im a bitch that dosent deserve to live

woah dude what????

 

[Biomaxx]

Im so insanely low iq, I cant source my own compounds and dont do my own research

Yeah ik dude

 

[Neurogenic]

Yeah ik dude

okay bhai do u have a source or nah

 

[Biomaxx]

okay bhai do u have a source or nah

Nah, decently hard to source becuase its new and only used in cancer trials

 

[Neurogenic]

Nah, decently hard to source becuase its new and only used in cancer trials

oh aight do you have any other FGFR3 inhibitor sources cuz the ones i found were super expsensive and idk if their even trustworthy

 

[Biomaxx]

oh aight do you have any other FGFR3 inhibitor sources cuz the ones i found were super expsensive and idk if their even trustworthy

t.me/lmpeptides
Say bio reffered you

 

[FoidSlayer]

t.me/lmpeptides
Say bio reffered you

Sup bio

 

[Biomaxx]

Sup bio

Sup lewis

 

[brownkeephittin]

Nga mirin ur high iq man , its over for ClosedGPcels.

 

[PrettyBoyMaxxing]

Zynx was old user here who straight hated me, pretty sure he was high iq

why was and not is?

 

[Biomaxx]

why was and not is?

Forgo this was ur new acc

 

[PrettyBoyMaxxing]

Forgo this was ur new acc

just changed name

 

[Biomaxx]

just changed name

Same as